| Bruce Willis | Tom Greer, FBI-agent |
| Radha Mitchell | Jennifer Peters, FBI-agent |
| Rosamund Pike | Maggie Greer, Toms fru |
| Boris Kodjoe | Andrew Stone, Toms och Jennifers chef |
| James Cromwell | doktor Lionel Canter, surrogaternas uppfinnare |
| James Francis Ginty | Lionel Canters yngre surrogat |
| Ving Rhames | The Prophet (Profeten) |
| Jack Noseworthy | Miles Strickland |
| Devin Ratray | Bobby |
| Michael Cudlitz | överste Brendon |
| Jeffrey De Serrano | Armando |
| Helena Mattsson | blondinen J.J. |
| Michael Phillip | uniformerad polis |
| Danny Smith | offer |
| Brian Parrish | Hard Hat |
| Jennifer Alden | hyresvärdinna |
| Shane Dzicek | Jarid Canter |